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Summary of the activity
The Pierre Louis Institute of Epidemiology and Public Health brings together all of the Sorbonne University’s epidemiology and public health research forces. The Institute covers the main fields of epidemiology, whether clinical, population or social, as well as pharmacoepidemiology, biostatistics, statistical and mathematical modelling, clinical research, the relationship between the environment and health, the social determinants of health and health care organizations. In terms of applications, we mainly deal with communicable diseases (influenza, HIV infection, viral hepatitis, etc.), nosocomial and emerging infections, chronic diseases (chronic inflammatory diseases, respiratory, allergic and cardiovascular diseases, psychiatric diseases), and care in intensive care.
Site/location and physical address
Saint-Antoine Hospital
Faculty of Medicine
Sorbonne University
27 rue de Chaligny – 75012 PARIS
Contact
Mail: u1136-contact@iplesp.upmc.fr
Phone:
+33 (0) 1 44 73 86 43
+33 (0)1 44 73 84 46
+33 (0)1 42 16 42 72
Guardianship
INSERM and Sorbonne University
Director / Head of structure
CARRAT Fabrice
COSTAGLIOLA Dominique
Research units
CLEPIVIR team: Clinical epidemiology of chronic viral diseases
The researchers of this team coordinate large thematic cohorts of people living with HIV, chronic viral hepatitis C, B and/or Delta, or HIV-hepatitis co-infection. They develop and use specific statistical methods to estimate the effect of treatments from observational data. The team’s scientific objectives are to quantify the benefits, risks and cost-effectiveness of antiviral management strategies for these chronic viral infections, to evaluate the co-morbidities induced by these infections or by the treatments – in particular cancers, cardiovascular or metabolic complications – and the strategies to prevent them. The team’s scientific objectives are to quantify the benefits, risks and cost-effectiveness of antiviral management strategies for these chronic viral infections, to evaluate the co-morbidities induced by these infections or by the treatments – in particular cancers, cardiovascular or metabolic complications – and the strategies to prevent them.
Website
https://www.iplesp.upmc.fr/fr/team/CLEPIVIR
Manager / Team Leader
Fabrice Carra
Team THERAVIR: Therapeutic strategies against HIV infection and associated viral diseases
The researchers of this team coordinate large thematic cohorts of people living with HIV, chronic viral hepatitis C, B and/or Delta, or HIV-hepatitis co-infection. They develop and use specific statistical methods to estimate the effect of treatments from observational data. The team’s scientific objectives are to quantify the benefits, risks and cost-effectiveness of antiviral management strategies for these chronic viral infections, to evaluate the co-morbidities induced by these infections or by the treatments – in particular cancers, cardiovascular or metabolic complications – and the strategies to prevent them. The team’s scientific objectives are to quantify the benefits, risks and cost-effectiveness of antiviral management strategies for these chronic viral infections, to evaluate the co-morbidities induced by these infections or by the treatments – in particular cancers, cardiovascular or metabolic complications – and the strategies to prevent them.
Website
https://www.iplesp.upmc.fr/fr/team/THERAVIR
Manager / Team Leader
Anne-Geneviève Marcellin
Christine Katlama
ERES team: Research team in social epidemiology
The general objectives of the ERES are to improve knowledge about the social determinants of health and to evaluate the impact of interventions and policies aimed at reducing social inequalities in health and access to care. The results produced by the ERES contribute to helping public health professionals and decision-makers adapt their practices in a context where, as in most industrialized countries, social inequalities in health have increased in recent years, despite a continuous increase in longevity. The specificity of our team is to include researchers specialized in the study of different aspects of health (cancer, mental health, addictions, screening and preventive practices) but also investigators, who have a broad perspective and focus on determinants of social inequalities in multiple domains of health (living areas, primary care) and/or particular populations (adolescents, pregnant women), some of which are hard to reach or marginalized (homeless people, immigrants). ERES has long-standing collaborations with clinicians (primary care, HIV, psychiatry), social scientists (sociology, geography, political science), and biostatisticians, both within and outside of IPLESP, creating an interdisciplinary environment.
Website
https://www.iplesp.upmc.fr/fr/team/ERES
Manager / Team Leader
Maria Melchior
Team SUMO – Surveillance and Modeling of Communicable Diseases
The “Surveillance and Modeling of Communicable Diseases” team brings together researchers specialized in the development of epidemiological information systems for the surveillance of communicable diseases and the analysis of their dissemination, particularly through modeling approaches. Communicable diseases remain a major public health problem. The different types of mobility, regional and global, allow an ever more rapid spread of infectious pathogens, creating the conditions for the emergence of new diseases. These phenomena are also supported by individual behavioral choices, from vaccine hesitancy reducing population protection to inappropriate antibiotic use increasing bacterial resistance.
Website
https://www.iplesp.upmc.fr/fr/team/SUMO
Manager / Team Leader
Pierre-Yves BOËLLE
NEMESIS Team: Environment, Mobility and Health
The two research objectives of the Nemesis team are to investigate how environments and neighborhoods affect health and to explore the impact of mobility and transportation on health. As for the first objective, our contribution is to investigate the contextual and environmental determinants of health behaviors and health using detailed spatio-temporal data. As for the second objective, we seek to develop a comprehensive model of the relationship between transportation and health integrating the physical activity benefits of active transportation but also the exposures to air pollutants and noise as well as the stress experienced in the different modes of transportation.
Website
https://www.iplesp.upmc.fr/fr/team/NEMESIS
Manager / Team Leader
Basile CHAIX
PEPITES team: Pharmacoepidemiology and evaluation of care
The scientific themes of the PEPITES team are pharmacoepidemiology (i.e. the evaluation of health products – drugs and medical devices – in real-life situations) and health care evaluation. More precisely, our research concerns populations at high risk due to specific characteristics (e.g. elderly people or patients in intensive care), the evaluation of the benefit/risk of biomedicines whatever the indication, the evaluation of the organization of care with a particular interest in the trajectories of patients and the key moments of transition (e.g. admission, the stay in the hospital proper or the discharge from the hospital and the transition with the city or the follow-up care) and their consequences on the benefit/risk of the health products.
Website
https://www.iplesp.upmc.fr/fr/team/PEPITES
Manager / Team Leader
Florence TUBACH